Once-Daily Tramadol

Tramadol Global Commercialization Program Our Product

We have developed and commercialized a once-daily formulation of the analgesic tramadol for the treatment of moderate to severe pain. Our once-daily tramadol product is an efficacious and safe option in the global landscape for analgesics.

Market Opportunity

The global market1 for tramadol products continues to experience robust growth, achieving a compounded annual growth rate of 13% over the last five years ended 2008. The market potential for our once-daily tramadol product, however, goes beyond that of the current tramadol market. Our product has the ability to compete in the broader market that addresses patients using combination opioids or tramadol/combination products, or those for whom NSAIDs and COX-2s are no longer appropriate – a group for whom 190 million prescriptions were written in the U.S. alone in 2008.

Status

Global Commercialization Underway - Launched in 19 countries, including the United States, Canada, major European markets and Australia

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1Based on standard units.